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Muscle lipogenesis balances insulin sensitivity and strength through calcium signaling

Exogenous dietary fat can induce obesity and promote diabetes, but endogenous fat production is not thought to affect skeletal muscle insulin resistance, an antecedent of metabolic disease. Unexpectedly, the lipogenic enzyme fatty acid synthase (FAS) was increased in the skeletal muscle of mice with...

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Détails bibliographiques
Auteurs principaux: Funai, Katsuhiko, Song, Haowei, Yin, Li, Lodhi, Irfan J., Wei, Xiaochao, Yoshino, Jun, Coleman, Trey, Semenkovich, Clay F.
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3582136/
https://ncbi.nlm.nih.gov/pubmed/23376793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI65726
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