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Mitochondrial complex I activity and NAD(+)/NADH balance regulate breast cancer progression
Despite advances in clinical therapy, metastasis remains the leading cause of death in breast cancer patients. Mutations in mitochondrial DNA, including those affecting complex I and oxidative phosphorylation, are found in breast tumors and could facilitate metastasis. This study identifies mitochon...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3582128/ https://ncbi.nlm.nih.gov/pubmed/23426180 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI64264 |
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