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Molecular remedy of complex I defects: Rotenone-insensitive internal NADH-quinone oxidoreductase of Saccharomyces cerevisiae mitochondria restores the NADH oxidase activity of complex I-deficient mammalian cells

The NDI1 gene encoding rotenone-insensitive internal NADH-quinone oxidoreductase of Saccharomyces cerevisiae mitochondria was cotransfected into the complex I-deficient Chinese hamster CCL16-B2 cells. Stable NDI1-transfected cells were obtained by screening with antibiotic G418. The NDI1 gene was sh...

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Detalhes bibliográficos
Main Authors: Seo, Byoung Boo, Kitajima-Ihara, Tomomi, Chan, Edward K. L., Scheffler, Immo E., Matsuno-Yagi, Akemi, Yagi, Takao
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1998
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC21310/
https://ncbi.nlm.nih.gov/pubmed/9689052
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