Characterization of the Ubiquinone Binding Site in Alternative NADH-Quinone Oxidoreductase of Saccharomyces cerevisiae by Photoaffinity Labeling

The Ndi1 enzyme found in the mitochondrial membrane of Saccharomyces cerevisiae is an NDH-2-type alternative NADH-quinone (Q) oxidoreductase. As Ndi1 is expected to be a possible remedy for complex I defects of mammalian mitochondria, a detailed biochemical characterization of the enzyme is needed....

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Auteurs principaux: Murai, Masatoshi, Yamashita, Tetsuo, Senoh, Mai, Mashimo, Yuko, Kataoka, Michihiko, Kosaka, Hiroaki, Matsuno-Yagi, Akemi, Yagi, Takao, Miyoshi, Hideto
Format: Artigo
Langue:Inglês
Publié: 2010
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847623/
https://ncbi.nlm.nih.gov/pubmed/20192260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100005j
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