Nicotinamide phosphoribosyltransferase can affect metastatic activity and cell adhesive functions by regulating integrins in breast cancer

NAD(+) metabolism is an essential regulator of cellular redox reactions, energy pathways, and a substrate provider for NAD(+) consuming enzymes. We recently demonstrated that enhancement of NAD(+)/NADH levels in breast cancer cells with impaired mitochondrial NADH dehydrogenase activity, through aug...

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Detalles Bibliográficos
Publicado en:DNA Repair (Amst)
Main Authors: Santidrian, Antonio F., LeBoeuf, Sarah E., Wold, Erik D., Ritland, Melissa, Forsyth, Jane S., Felding, Brunhilde H.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4252795/
https://ncbi.nlm.nih.gov/pubmed/25263164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2014.08.006
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