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Parkinson’s disease and mitochondrial complex I: a perspective on the Ndi1 therapy

Mitochondrial impairment has been collecting more and more attention as a contributing factor to the etiology of Parkinson’s disease. Above all, the NADH-quinone oxidoreductase, complex I, of the respiratory chain seems to be most culpable. Complex I dysfunction is translated to an increased product...

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Main Authors: Marella, Mathieu, Seo, Byoung Boo, Yagi, Takao, Matsuno-Yagi, Akemi
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2924754/
https://ncbi.nlm.nih.gov/pubmed/19904590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10863-009-9249-z
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