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Amplification of GC-rich DNA for high-throughput family based genetic studies

Researchers face a significant problem in PCR amplification of DNA fragments with high GC contents. Analysis of these regions is of importance since many regulatory regions of different genes and their first exons are GC-rich. There are a large number of protocols for amplification of GC-rich DNA, s...

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Detalhes bibliográficos
Main Authors: Naz, Sadaf, Fatima, Amara
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581729/
https://ncbi.nlm.nih.gov/pubmed/22644933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12033-012-9559-y
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