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Effect of Surface Coating with Magnesium Stearate via Mechanical Dry Powder Coating Approach on the Aerosol Performance of Micronized Drug Powders from Dry Powder Inhalers

The objective of this study was to investigate the effect of particle surface coating with magnesium stearate on the aerosolization of dry powder inhaler formulations. Micronized salbutamol sulphate as a model drug was dry coated with magnesium stearate using a mechanofusion technique. The coating q...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhou, Qi (Tony), Qu, Li, Gengenbach, Thomas, Larson, Ian, Stewart, Peter J., Morton, David A. V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer US 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581661/
https://ncbi.nlm.nih.gov/pubmed/23196863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-012-9895-z
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