Cathepsin B and uPAR regulate self-renewal of glioma-initiating cells through GLI-regulated Sox2 and Bmi1 expression

Cancer-initiating cells comprise a heterogeneous population of undifferentiated cells with the capacity for self-renewal and high proliferative potential. We investigated the role of uPAR and cathepsin B in the maintenance of stem cell nature in glioma-initiating cells (GICs). Simultaneous knockdown...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Gopinath, Sreelatha, Malla, RamaRao, Alapati, Kiranmai, Gorantla, Bharathi, Gujrati, Meena, Dinh, Dzung H., Rao, Jasti S.
פורמט: Artigo
שפה:Inglês
יצא לאור: Oxford University Press 2013
נושאים:
Original Manuscript
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581601/
https://ncbi.nlm.nih.gov/pubmed/23222817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgs375
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!

פריטים דומים