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Proprotein Convertases Process and Thereby Inactivate Formylglycine-generating Enzyme

Formylglycine-generating enzyme (FGE) post-translationally converts a specific cysteine in newly synthesized sulfatases to formylglycine (FGly). FGly is the key catalytic residue of the sulfatase family, comprising 17 nonredundant enzymes in human that play essential roles in development and homeost...

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Détails bibliographiques
Auteurs principaux: Ennemann, Eva C., Radhakrishnan, Karthikeyan, Mariappan, Malaiyalam, Wachs, Michaela, Pringle, Thomas H., Schmidt, Bernhard, Dierks, Thomas
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2013
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581403/
https://ncbi.nlm.nih.gov/pubmed/23288839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.405159
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