Inhibition of Class I Histone Deacetylases Unveils a Mitochondrial Signature and Enhances Oxidative Metabolism in Skeletal Muscle and Adipose Tissue

Chromatin modifications are sensitive to environmental and nutritional stimuli. Abnormalities in epigenetic regulation are associated with metabolic disorders such as obesity and diabetes that are often linked with defects in oxidative metabolism. Here, we evaluated the potential of class-specific s...

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Detalhes bibliográficos
Main Authors: Galmozzi, Andrea, Mitro, Nico, Ferrari, Alessandra, Gers, Elise, Gilardi, Federica, Godio, Cristina, Cermenati, Gaia, Gualerzi, Alice, Donetti, Elena, Rotili, Dante, Valente, Sergio, Guerrini, Uliano, Caruso, Donatella, Mai, Antonello, Saez, Enrique, De Fabiani, Emma, Crestani, Maurizio
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2013
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581211/
https://ncbi.nlm.nih.gov/pubmed/23069623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-0548
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