Inhibition of Class I Histone Deacetylases Unveils a Mitochondrial Signature and Enhances Oxidative Metabolism in Skeletal Muscle and Adipose Tissue

Chromatin modifications are sensitive to environmental and nutritional stimuli. Abnormalities in epigenetic regulation are associated with metabolic disorders such as obesity and diabetes that are often linked with defects in oxidative metabolism. Here, we evaluated the potential of class-specific s...

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Main Authors: Galmozzi, Andrea, Mitro, Nico, Ferrari, Alessandra, Gers, Elise, Gilardi, Federica, Godio, Cristina, Cermenati, Gaia, Gualerzi, Alice, Donetti, Elena, Rotili, Dante, Valente, Sergio, Guerrini, Uliano, Caruso, Donatella, Mai, Antonello, Saez, Enrique, De Fabiani, Emma, Crestani, Maurizio
Format: Artigo
Sprog:Inglês
Udgivet: American Diabetes Association 2013
Fag:
Metabolism
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581211/
https://ncbi.nlm.nih.gov/pubmed/23069623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-0548
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