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CpG Island Hypermethylation Frequently Silences FILIP1L Isoform 2 Expression in Prostate Cancer

PURPOSE: Senescence related regulatory pathways serve as barriers to cancer immortalization and progression but they are currently not well defined. FILIP1L is a growth inhibitory gene with multiple isoforms whose expression is increased in senescent prostate and prostate cancer cells, and decreased...

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Detalhes bibliográficos
Main Authors: Desotelle, Joshua, Truong, Matthew, Ewald, Jonathan, Weeratunga, Pushpa, Yang, Bing, Huang, Wei, Jarrard, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581042/
https://ncbi.nlm.nih.gov/pubmed/23174249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.juro.2012.08.188
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