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The Potent Human Immunodeficiency Virus Type 1 (HIV-1) Entry Inhibitor HR212 Blocks Formation of the Envelope Glycoprotein gp41 Six-Helix Bundle

HR212, a recombinant protein composed of the heptad repeat, is a rationally designed human immunodeficiency virus type 1 (HIV-1) fusion inhibitor. This protein can be easily produced by Escherichia coli at a low cost. Previously, studies indicated that HR212 can efficiently inhibit the entry and rep...

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Autors principals: Ouyang, Wenjie, An, Tai, Guo, Deyin, Wu, Shuwen, Tien, Po
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581026/
https://ncbi.nlm.nih.gov/pubmed/23308369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2012.0059
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