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N-Substituted Pyrrole Derivative 12m Inhibits HIV-1 Entry by Targeting Gp41 of HIV-1 Envelope Glycoprotein

The combination of three or more antiviral agents that act on different targets is known as highly active antiretroviral therapy (HAART), which is widely used to control HIV infection. However, because drug resistance and adverse effects occur after long-term administration, an increasing number of...

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Détails bibliographiques
Publié dans:Front Pharmacol
Auteurs principaux: Qiu, Jiayin, Liang, Taizhen, Wu, Junyan, Yu, Fei, He, Xiaoyang, Tian, Yuanxin, Xie, Lan, Jiang, Shibo, Liu, Shuwen, Li, Lin
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6688628/
https://ncbi.nlm.nih.gov/pubmed/31427969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00859
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