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N-Substituted Pyrrole Derivative 12m Inhibits HIV-1 Entry by Targeting Gp41 of HIV-1 Envelope Glycoprotein

The combination of three or more antiviral agents that act on different targets is known as highly active antiretroviral therapy (HAART), which is widely used to control HIV infection. However, because drug resistance and adverse effects occur after long-term administration, an increasing number of...

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Publicado en:Front Pharmacol
Main Authors: Qiu, Jiayin, Liang, Taizhen, Wu, Junyan, Yu, Fei, He, Xiaoyang, Tian, Yuanxin, Xie, Lan, Jiang, Shibo, Liu, Shuwen, Li, Lin
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6688628/
https://ncbi.nlm.nih.gov/pubmed/31427969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00859
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