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Metformin overdose, but not lactic acidosis per se, inhibits oxygen consumption in pigs
INTRODUCTION: Hepatic mitochondrial dysfunction may play a critical role in the pathogenesis of metformin-induced lactic acidosis. However, patients with severe metformin intoxication may have a 30 to 60% decrease in their global oxygen consumption, as for generalized inhibition of mitochondrial res...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3580617/ https://ncbi.nlm.nih.gov/pubmed/22568883 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc11332 |
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