Metformin overdose causes platelet mitochondrial dysfunction in humans

INTRODUCTION: We have recently demonstrated that metformin intoxication causes mitochondrial dysfunction in several porcine tissues, including platelets. The aim of the present work was to clarify whether it also causes mitochondrial dysfunction (and secondary lactate overproduction) in human platel...

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Detalhes bibliográficos
Main Authors: Protti, Alessandro, Lecchi, Anna, Fortunato, Francesco, Artoni, Andrea, Greppi, Noemi, Vecchio, Sarah, Fagiolari, Gigliola, Moggio, Maurizio, Comi, Giacomo Pietro, Mistraletti, Giovanni, Lanticina, Barbara, Faraldi, Loredana, Gattinoni, Luciano
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682281/
https://ncbi.nlm.nih.gov/pubmed/23034133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc11663
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