Metformin overdose causes platelet mitochondrial dysfunction in humans

INTRODUCTION: We have recently demonstrated that metformin intoxication causes mitochondrial dysfunction in several porcine tissues, including platelets. The aim of the present work was to clarify whether it also causes mitochondrial dysfunction (and secondary lactate overproduction) in human platel...

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Autors principals: Protti, Alessandro, Lecchi, Anna, Fortunato, Francesco, Artoni, Andrea, Greppi, Noemi, Vecchio, Sarah, Fagiolari, Gigliola, Moggio, Maurizio, Comi, Giacomo Pietro, Mistraletti, Giovanni, Lanticina, Barbara, Faraldi, Loredana, Gattinoni, Luciano
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682281/
https://ncbi.nlm.nih.gov/pubmed/23034133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc11663
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