Metformin overdose causes platelet mitochondrial dysfunction in humans

INTRODUCTION: We have recently demonstrated that metformin intoxication causes mitochondrial dysfunction in several porcine tissues, including platelets. The aim of the present work was to clarify whether it also causes mitochondrial dysfunction (and secondary lactate overproduction) in human platel...

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Detaylı Bibliyografya
Asıl Yazarlar: Protti, Alessandro, Lecchi, Anna, Fortunato, Francesco, Artoni, Andrea, Greppi, Noemi, Vecchio, Sarah, Fagiolari, Gigliola, Moggio, Maurizio, Comi, Giacomo Pietro, Mistraletti, Giovanni, Lanticina, Barbara, Faraldi, Loredana, Gattinoni, Luciano
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2012
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682281/
https://ncbi.nlm.nih.gov/pubmed/23034133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc11663
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