Atorvastatin inhibits osteoclastogenesis by decreasing the expression of RANKL in the synoviocytes of rheumatoid arthritis

INTRODUCTION: Statins, hydroxymethylglutaryl-coenzyme A reductase inhibitors, have been reported to have antiinflammatory and/or immunomodulatory effects and prophylactic and therapeutic effects in collagen-induced arthritis, an experimental model of rheumatoid arthritis (RA). The authors undertook...

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Autori principali: Kim, Jeong Yeon, Lee, Eun Young, Lee, Eun Bong, Lee, Yun Jong, Yoo, Hyun Jung, Choi, Jiyong, Song, Yeong Wook
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3580583/
https://ncbi.nlm.nih.gov/pubmed/22901757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar4018
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