Macrophage migration inhibitory factor enhances osteoclastogenesis through upregulation of RANKL expression from fibroblast-like synoviocytes in patients with rheumatoid arthritis

INTRODUCTION: Macrophage migration inhibitory factor (MIF) is one of key regulators in acute and chronic immune-inflammatory conditions including rheumatoid arthritis (RA). We examined the effect of MIF on osteoclastogenesis, which is known to play a crucial role in bone destruction in RA. METHODS:...

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Hlavní autoři: Kim, Hae-Rim, Kim, Kyoung-Woon, Jung, Hong Geun, Yoon, Kwang-Sup, Oh, Hye-Jwa, Cho, Mi-La, Lee, Sang-Heon
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2011
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3132025/
https://ncbi.nlm.nih.gov/pubmed/21401926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3279
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