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N-acetyl-l-cysteine controls osteoclastogenesis through regulating Th17 differentiation and RANKL in rheumatoid arthritis

BACKGROUND/AIMS: This study aimed to determine the regulatory role of N-acetyl-l-cysteine (NAC), an antioxidant, in interleukin 17 (IL-17)-induced osteoclast differentiation in rheumatoid arthritis (RA). METHODS: After RA synovial fibroblasts were stimulated by IL-17, the expression and production o...

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Detalhes bibliográficos
Publicado no:Korean J Intern Med
Main Authors: Kim, Hae-Rim, Kim, Kyoung-Woon, Kim, Bo-Mi, Lee, Kyung-Ann, Lee, Sang-Heon
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Association of Internal Medicine 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6325425/
https://ncbi.nlm.nih.gov/pubmed/28286938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3904/kjim.2016.329
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