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Real-time monitoring of tyrosine hydroxylase activity using a plate reader assay
Tyrosine hydroxylase (TH) is the rate-limiting step in dopamine (DA) synthesis, oxidizing tyrosine to l-DOPA, which is further metabolized to DA. Current assays for monitoring activity of this enzyme require extensive work-up, require long analysis time, and measure end points, thereby lacking real-...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3579528/ https://ncbi.nlm.nih.gov/pubmed/23010244 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2012.09.005 |
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