Manganese Supplementation Protects Against Diet-Induced Diabetes in Wild Type Mice by Enhancing Insulin Secretion

Mitochondrial dysfunction is both a contributing mechanism and complication of diabetes, and oxidative stress contributes to that dysfunction. Mitochondrial manganese-superoxide dismutase (MnSOD) is a metalloenzyme that provides antioxidant protection. We have previously shown in a mouse model of he...

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Bibliographic Details
Main Authors: Lee, Soh-Hyun, Jouihan, Hani A., Cooksey, Robert C., Jones, Deborah, Kim, Hyung J., Winge, Dennis R., McClain, Donald A.
Format: Artigo
Language:Inglês
Published: Endocrine Society 2013
Subjects:
Diabetes-Insulin-Glucagon-Gastrointestinal
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3578995/
https://ncbi.nlm.nih.gov/pubmed/23372018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2012-1445
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