Iron-Mediated Inhibition of Mitochondrial Manganese Uptake Mediates Mitochondrial Dysfunction in a Mouse Model of Hemochromatosis

Previous phenotyping of glucose homeostasis and insulin secretion in a mouse model of hereditary hemochromatosis (Hfe(−/−)) and iron overload suggested mitochondrial dysfunction. Mitochondria from Hfe(−/−) mouse liver exhibited decreased respiratory capacity and increased lipid peroxidation. Althoug...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Jouihan, Hani A, Cobine, Paul A, Cooksey, Robert C, Hoagland, Emily A, Boudina, Sihem, Abel, E Dale, Winge, Dennis R, McClain, Donald A
Médium: Artigo
Jazyk:Inglês
Vydáno: ScholarOne 2008
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258172/
https://ncbi.nlm.nih.gov/pubmed/18317567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/2007-00114.Jouihan
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky