T Cell Hypo-Responsiveness against Leishmania major in MAP Kinase Phosphatase (MKP) 2 Deficient C57BL/6 Mice Does Not Alter the Healer Disease Phenotype

We have recently demonstrated that MAP kinase phosphatase 2 (MKP-2) deficient C57BL/6 mice, unlike their wild-type counterparts, are unable to control infection with the protozoan parasite Leishmania mexicana. Increased susceptibility was associated with elevated Arginase-1 levels and reduced iNOS a...

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Autores principales: Schroeder, Juliane, McGachy, H. Adrienne, Woods, Stuart, Plevin, Robin, Alexander, James
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3578781/
https://ncbi.nlm.nih.gov/pubmed/23437409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0002064
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