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Significantly Improved HIV Inhibitor Efficacy Prediction Employing Proteochemometric Models Generated From Antivirogram Data

Infection with HIV cannot currently be cured; however it can be controlled by combination treatment with multiple anti-retroviral drugs. Given different viral genotypes for virtually each individual patient, the question now arises which drug combination to use to achieve effective treatment. With t...

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Hlavní autoři: van Westen, Gerard J. P., Hendriks, Alwin, Wegner, Jörg K., IJzerman, Adriaan P., van Vlijmen, Herman W. T., Bender, Andreas
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3578754/
https://ncbi.nlm.nih.gov/pubmed/23436985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002899
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