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Cutting Edge: Impaired MHC Class I Expression in Mice Deficient for Nlrc5/CITA

MHC class I and class II are crucial for the adaptive immune system. Although regulation of MHC class II expression by CIITA (class II transactivator) has long been recognized, the mechanism of MHC class I transactivation has been largely unknown until the recent discovery of NLRC5/CITA. Here we sho...

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Main Authors: Biswas, Amlan, Meissner, Torsten B., Taro Kawai, Kobayashi, Koichi S.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3578426/
https://ncbi.nlm.nih.gov/pubmed/22711889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200064
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