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NLR family member NLRC5 is a transcriptional regulator of MHC class I genes
MHC class I plays a critical role in the immune defense against viruses and tumors by presenting antigens to CD8 T cells. An NLR protein, class II transactivator (CIITA), is a key regulator of MHC class II gene expression that associates and cooperates with transcription factors in the MHC class II...
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| Hlavní autoři: | , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2010
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2922274/ https://ncbi.nlm.nih.gov/pubmed/20639463 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1008684107 |
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