NLR family member NLRC5 is a transcriptional regulator of MHC class I genes

MHC class I plays a critical role in the immune defense against viruses and tumors by presenting antigens to CD8 T cells. An NLR protein, class II transactivator (CIITA), is a key regulator of MHC class II gene expression that associates and cooperates with transcription factors in the MHC class II...

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Bibliografiske detaljer
Main Authors: Meissner, Torsten B., Li, Amy, Biswas, Amlan, Lee, Kyoung-Hee, Liu, Yuen-Joyce, Bayir, Erkan, Iliopoulos, Dimitrios, van den Elsen, Peter J., Kobayashi, Koichi S.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2010
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922274/
https://ncbi.nlm.nih.gov/pubmed/20639463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1008684107
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