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NLRC5 cooperates with the RFX transcription factor complex to induce MHC class I gene expression
Tight regulation of MHC class I gene expression is critical for CD8 T cell activation and host adaptive immune responses. The promoters of MHC class I genes contain a well-conserved core module, the W/S-X-Y motif, which assembles a nucleoprotein complex termed MHC-enhanceosome. A member of the NLR (...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3345046/ https://ncbi.nlm.nih.gov/pubmed/22490869 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103160 |
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