Live Attenuated Leishmania donovani p27 Gene Knockout Parasites Are Non-pathogenic and Elicit Long Term Protective Immunity in BALB/c Mice

Leishmaniasis causes significant morbidity and mortality worldwide and there are no vaccines available against this disease. Previously, we had shown that the amastigote specific protein p27 (Ldp27) is a component of an active cytochrome c oxidase complex in L. donovani and upon deletion of its gene...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Dey, Ranadhir, Dagur, Pradeep K., Selvapandiyan, Angamuthu, McCoy, J. Philip, Salotra, Poonam, Duncan, Robert, Nakhasi, Hira L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3578143/
https://ncbi.nlm.nih.gov/pubmed/23338240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202801
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky