Gene deleted live attenuated Leishmania vaccine candidates against visceral leishmaniasis elicit pro-inflammatory cytokines response in human PBMCs

Currently no effective vaccine is available for human visceral leishmaniasis(VL) caused by Leishmania donovani. Previously, we showed that centrin1 and p27gene deleted live attenuated Leishmania parasites (LdCen1(−/−) and Ldp27(−/−)) are safe, immunogenic and protective in animal models. Here, to as...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Avishek, Kumar, Kaushal, Himanshu, Gannavaram, Sreenivas, Dey, Ranadhir, Selvapandiyan, Angamuthu, Ramesh, V., Negi, Narender Singh, Dubey, Uma S., Nakhasi, Hira L., Salotra, Poonam
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5021981/
https://ncbi.nlm.nih.gov/pubmed/27624408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep33059
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