Gene deleted live attenuated Leishmania vaccine candidates against visceral leishmaniasis elicit pro-inflammatory cytokines response in human PBMCs

Currently no effective vaccine is available for human visceral leishmaniasis(VL) caused by Leishmania donovani. Previously, we showed that centrin1 and p27gene deleted live attenuated Leishmania parasites (LdCen1(−/−) and Ldp27(−/−)) are safe, immunogenic and protective in animal models. Here, to as...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:Sci Rep
المؤلفون الرئيسيون: Avishek, Kumar, Kaushal, Himanshu, Gannavaram, Sreenivas, Dey, Ranadhir, Selvapandiyan, Angamuthu, Ramesh, V., Negi, Narender Singh, Dubey, Uma S., Nakhasi, Hira L., Salotra, Poonam
التنسيق: Artigo
اللغة:Inglês
منشور في: Nature Publishing Group 2016
الموضوعات:
Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC5021981/
https://ncbi.nlm.nih.gov/pubmed/27624408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep33059
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