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Vibriocholerae cytolysin recognizes the heptasaccharide core of complex N-glycans with nanomolar affinity

Pathogens selectively target host cells using adhesion molecules and secreted virulence factors that may utilize protein, lipid, or carbohydrate ligands on the cell surface. The human intestinal pathogen Vibrio cholerae secretes a pore-forming toxin, Vibrio cholerae cytolysin (VCC), which contains t...

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Autors principals: Levan, Sophia, De, Swastik, Olson, Rich
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3578121/
https://ncbi.nlm.nih.gov/pubmed/23274141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2012.12.016
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