The Relationship between Glycan Binding and Direct Membrane Interactions in Vibrio cholerae Cytolysin, a Channel-forming Toxin

Bacterial pore-forming toxins (PFTs) are structurally diverse pathogen-secreted proteins that form cell-damaging channels in the membranes of host cells. Most PFTs are released as water-soluble monomers that first oligomerize on the membrane before inserting a transmembrane channel. To modulate spec...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: De, Swastik, Bubnys, Adele, Alonzo, Francis, Hyun, Jinsol, Lary, Jeffrey W., Cole, James L., Torres, Victor J., Olson, Rich
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4653697/
https://ncbi.nlm.nih.gov/pubmed/26416894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.675967
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