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Crystal structure of the Vibrio cholerae cytolysin heptamer reveals common features among disparate pore-forming toxins

Pore-forming toxins (PFTs) are potent cytolytic agents secreted by pathogenic bacteria that protect microbes against the cell-mediated immune system (by targeting phagocytic cells), disrupt epithelial barriers, and liberate materials necessary to sustain growth and colonization. Produced by gram-pos...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: De, Swastik, Olson, Rich
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088620/
https://ncbi.nlm.nih.gov/pubmed/21502531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1017442108
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