A new structural paradigm in copper resistance in Streptococcus pneumoniae

Copper resistance has emerged as an important virulence determinant of microbial pathogens. In Streptococcus pneumoniae, copper resistance is mediated by the copper-responsive repressor CopY, CupA, and CopA, a copper effluxing P(1B)-type ATPase. We show here that CupA is a novel cell membrane-anchor...

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Hoofdauteurs: Fu, Yue, Tsui, Ho-Ching Tiffany, Bruce, Kevin E., Sham, Lok-To, Higgins, Khadine A., Lisher, John P., Kazmierczak, Krystyna M., Maroney, Michael J., Dann, Charles E., Winkler, Malcolm E., Giedroc, David P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3578076/
https://ncbi.nlm.nih.gov/pubmed/23354287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1168
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