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Physical Characterization of the Manganese-sensing Pneumococcal Surface Antigen Repressor (PsaR) from Streptococcus pneumoniae*

Transition metals, including manganese, are required for proper virulence and persistence of many pathogenic bacteria. In Streptococcus pneumoniae (Spn), manganese homeostasis is controlled by a high affinity Mn(II) uptake complex, PsaBCA, and a constitutively expressed efflux transporter, MntE. Psa...

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Detalhes bibliográficos
Main Authors: Lisher, John P., Higgins, Khadine A., Maroney, Michael J., Giedroc, David P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3859839/
https://ncbi.nlm.nih.gov/pubmed/24067066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi401132w
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