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Interplay between manganese and zinc homeostasis in the human pathogen Streptococcus pneumoniae

ICP-MS analysis of Streptococcus pneumoniae reveals a high cell-associated Mn(II) concentration that is comparable to that of Zn(II). Stressing these cells with 100–200 μM Zn(II) leads to a slow-growth phenotype and a total Mn(II) concentration that is reduced, with no decrease of other metal ions....

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Bibliographic Details
Main Authors: Jacobsen, Faith E., Kazmierczak, Krystyna M., Lisher, John P., Winkler, Malcolm E., Giedroc, David P.
Format: Artigo
Language:Inglês
Published: 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3061551/
https://ncbi.nlm.nih.gov/pubmed/21275153
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