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Intracellular calcium release modulates polycystin-2 trafficking
BACKGROUND: Polycystin-2 (PC2), encoded by the gene that is mutated in autosomal dominant polycystic kidney disease (ADPKD), functions as a calcium (Ca(2+)) permeable ion channel. Considerable controversy remains regarding the subcellular localization and signaling function of PC2 in kidney cells. M...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3577431/ https://ncbi.nlm.nih.gov/pubmed/23398808 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2369-14-34 |
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