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Intracellular Zinc Modulates Cardiac Ryanodine Receptor-mediated Calcium Release
Aberrant Zn(2+) homeostasis is a hallmark of certain cardiomyopathies associated with altered contractile force. In this study, we addressed whether Zn(2+) modulates cardiac ryanodine receptor gating and Ca(2+) dynamics in isolated cardiomyocytes. We reveal that Zn(2+) is a high affinity regulator o...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4498093/ https://ncbi.nlm.nih.gov/pubmed/26041778 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.661280 |
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