Caspofungin Modulates Ryanodine Receptor-Mediated Calcium Release in Human Cardiac Myocytes

Recent studies showed that critically ill patients might be at risk for hemodynamic impairment during caspofungin (CAS) therapy. The aim of our present study was to examine the mechanisms behind CAS-induced cardiac alterations. We revealed a dose-dependent increase in intracellular Ca(2+) concentrat...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Antimicrob Agents Chemother
Prif Awduron: Koch, Christian, Jersch, Jennifer, Schneck, Emmanuel, Edinger, Fabian, Maxeiner, Hagen, Uhle, Florian, Weigand, Markus A., Markmann, Melanie, Sander, Michael, Henrich, Michael
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2018
Pynciau:
Mechanisms of Action: Physiological Effects
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6201063/
https://ncbi.nlm.nih.gov/pubmed/30150463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01114-18
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