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Caspofungin Modulates Ryanodine Receptor-Mediated Calcium Release in Human Cardiac Myocytes

Recent studies showed that critically ill patients might be at risk for hemodynamic impairment during caspofungin (CAS) therapy. The aim of our present study was to examine the mechanisms behind CAS-induced cardiac alterations. We revealed a dose-dependent increase in intracellular Ca(2+) concentrat...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Koch, Christian, Jersch, Jennifer, Schneck, Emmanuel, Edinger, Fabian, Maxeiner, Hagen, Uhle, Florian, Weigand, Markus A., Markmann, Melanie, Sander, Michael, Henrich, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6201063/
https://ncbi.nlm.nih.gov/pubmed/30150463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01114-18
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