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Caspofungin induces the release of Ca(2+) ions from internal stores by activating ryanodine receptor-dependent pathways in human tracheal epithelial cells

The antimycotic drug caspofungin is known to alter the cell function of cardiomyocytes and the cilia-bearing cells of the tracheal epithelium. The objective of this study was to investigate the homeostasis of intracellular Ca(2+) concentration ([Ca(2+)](i)) after exposure to caspofungin in isolated...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Müller, Sabrina, Koch, Christian, Weiterer, Sebastian, Weigand, Markus A., Sander, Michael, Henrich, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7367263/
https://ncbi.nlm.nih.gov/pubmed/32678179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-68626-7
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