Ouabain, a steroid hormone that signals with slow calcium oscillations

The plant-derived steroid, digoxin, a specific inhibitor of Na,K-ATPase, has been used for centuries in the treatment of heart disease. Recent studies demonstrate the presence of a digoxin analog, ouabain, in mammalian tissue, but its biological role has not been elucidated. Here, we show in renal e...

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Bibliografiske detaljer
Main Authors: Aizman, Oleg, Uhlén, Per, Lal, Mark, Brismar, Hjalmar, Aperia, Anita
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 2001
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC60886/
https://ncbi.nlm.nih.gov/pubmed/11687608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.221315298
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