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Intracellular calcium release modulates polycystin-2 trafficking

BACKGROUND: Polycystin-2 (PC2), encoded by the gene that is mutated in autosomal dominant polycystic kidney disease (ADPKD), functions as a calcium (Ca(2+)) permeable ion channel. Considerable controversy remains regarding the subcellular localization and signaling function of PC2 in kidney cells. M...

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Detalhes bibliográficos
Main Authors: Miyakawa, Ayako, Ibarra, Cristián, Malmersjö, Seth, Aperia, Anita, Wiklund, Peter, Uhlén, Per
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3577431/
https://ncbi.nlm.nih.gov/pubmed/23398808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2369-14-34
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