Loading...
The Role of Tyrosine 71 in Modulating the Flap Conformations of BACE1
β-site amyloid precursor protein cleaving enzyme 1 (BACE1) is a potential target for treating Alzheimer’s disease. BACE1’s binding site is partially covered by a flexible loop on its N-terminal domain, known as the “flap,” which has been found in several conformations in crystal structures of BACE1...
Na minha lista:
| Main Authors: | , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3577374/ https://ncbi.nlm.nih.gov/pubmed/21590744 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.23050 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|