Single-Molecule Imaging Reveals Aβ42:Aβ40 Ratio-Dependent Oligomer Growth on Neuronal Processes

Soluble oligomers of the amyloid-β peptide have been implicated as proximal neurotoxins in Alzheimer’s disease. However, the identity of the neurotoxic aggregate(s) and the mechanisms by which these species induce neuronal dysfunction remain uncertain. Physiologically relevant experimentation is hin...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Johnson, Robin D., Schauerte, Joseph A., Chang, Chun-Chieh, Wisser, Kathleen C., Althaus, John Christian, Carruthers, Cynthia J.L., Sutton, Michael A., Steel, Duncan G., Gafni, Ari
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Biophysical Society 2013
Gaiak:
Proteins and Nucleic Acids
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3576537/
https://ncbi.nlm.nih.gov/pubmed/23442968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.12.051
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