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Direct Observation of Single Amyloid-β(1-40) Oligomers on Live Cells: Binding and Growth at Physiological Concentrations

Understanding how amyloid-β peptide interacts with living cells on a molecular level is critical to development of targeted treatments for Alzheimer's disease. Evidence that oligomeric Aβ interacts with neuronal cell membranes has been provided, but the mechanism by which membrane binding occur...

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Detalles Bibliográficos
Main Authors: Johnson, Robin D., Schauerte, Joseph A., Wisser, Kathleen C., Gafni, Ari, Steel, Duncan G.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3162019/
https://ncbi.nlm.nih.gov/pubmed/21901146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023970
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