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Simultaneous Single Molecule Fluorescence and Conductivity Studies Reveal Distinct Classes of Aβ Species on Lipid Bilayers

The extracellular senile plaques prevalent in brain tissue in Alzheimer's disease (AD) are composed of amyloid fibrils formed by the Aβ peptide. These fibrils have been traditionally believed to feature in neurotoxicity; however, numerous recent studies provide evidence that cytotoxicity in AD...

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Detalhes bibliográficos
Main Authors: Schauerte, Joseph A., Wong, Pamela T., Wisser, Kathleen C., Ding, Hao, Steel, Duncan G., Gafni, Ari
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2862386/
https://ncbi.nlm.nih.gov/pubmed/20201586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901444w
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