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Simultaneous Single Molecule Fluorescence and Conductivity Studies Reveal Distinct Classes of Aβ Species on Lipid Bilayers

The extracellular senile plaques prevalent in brain tissue in Alzheimer's disease (AD) are composed of amyloid fibrils formed by the Aβ peptide. These fibrils have been traditionally believed to feature in neurotoxicity; however, numerous recent studies provide evidence that cytotoxicity in AD...

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Bibliographische Detailangaben
Hauptverfasser: Schauerte, Joseph A., Wong, Pamela T., Wisser, Kathleen C., Ding, Hao, Steel, Duncan G., Gafni, Ari
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2862386/
https://ncbi.nlm.nih.gov/pubmed/20201586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901444w
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