Single-Molecule Imaging Reveals Aβ42:Aβ40 Ratio-Dependent Oligomer Growth on Neuronal Processes

Soluble oligomers of the amyloid-β peptide have been implicated as proximal neurotoxins in Alzheimer’s disease. However, the identity of the neurotoxic aggregate(s) and the mechanisms by which these species induce neuronal dysfunction remain uncertain. Physiologically relevant experimentation is hin...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Johnson, Robin D., Schauerte, Joseph A., Chang, Chun-Chieh, Wisser, Kathleen C., Althaus, John Christian, Carruthers, Cynthia J.L., Sutton, Michael A., Steel, Duncan G., Gafni, Ari
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2013
Assuntos:
Proteins and Nucleic Acids
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3576537/
https://ncbi.nlm.nih.gov/pubmed/23442968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.12.051
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados