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Synergistic Interactions between Alzheimer’s Aβ40 and Aβ42 on the Surface of Primary Neurons Revealed by Single Molecule Microscopy

Two amyloid-β peptides (Aβ40 and Aβ42) feature prominently in the extracellular brain deposits associated with Alzheimer’s disease. While Aβ40 is the prevalent form in the cerebrospinal fluid, the fraction of Aβ42 increases in the amyloid deposits over the course of disease development. The low in v...

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Autors principals: Chang, Chun-Chieh, Althaus, John Christian, Carruthers, Cynthia J. L., Sutton, Michael A., Steel, Duncan G., Gafni, Ari
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3847093/
https://ncbi.nlm.nih.gov/pubmed/24312636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082139
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